N-Fluorobenzenesulfonimide (NFSI) CAS 133745-75-2 Purity >98.0% (HPLC) Fluorinating Reagent

N-Fluorobenzenesulfonimide Synonyms: NFSI; Accufluor NFSi  CAS: 133745-75-2 Purity: >98.0% (HPLC) Appearance: White to Off-White Crystal Fluorinating Reagent, High Quality  Contact: Dr. Alvin Huang Mobile/Wechat/WhatsApp: +86-15026746401 E-Mail: alvin@ruifuchem.com

Products Details

Chemical Properties:

Package: Bottle, Aluminium foil bag, 25kg/Cardboard Drum, or according to customer's requirement. Storage Condition: Store in a tightly closed container. Store in a cool, dry (2~8℃) and well-ventilated warehouse away from incompatible substances. Protect from light and moisture. Incompatible with oxidizing agents. Shipping: Deliver to worldwide by air, by FedEx / DHL Express. Provide fast and reliable delivery. Shanghai Ruifu Chemical Co., Ltd. is the leading manufacturer of N-Fluorobenzenesulfonimide (NFSI) (CAS: 133745-75-2) with high quality. Ruifu Chemical can provide worldwide delivery, competitive price, excellent service, small and bulk quantities available. Purchase N-Fluorobenzenesulfonimide, Please contact: alvin@ruifuchem.com

Description:

Package/Storage/Shipping:

Chemical Name N-Fluorobenzenesulfonimide 
Synonyms NFSI; Accufluor NFSi; NFBS; N-Fluorobis(phenylsulfonyl)amine; N-Fluorodi(benzenesulfonyl)amine; N-Fluorodibenzenesulfonimide
Stock Status In Stock, Commercial Scale
CAS Number 133745-75-2
Molecular Formula C12H10FNO4S2 
Molecular Weight 315.33 g/mol
Melting Point 114.0 to 119.0℃ 
Solubility  Very Soluble in Acetonitrile, Dichloromethane or THF
Storage Temp.  Cool & Dry Place (2~8℃) 
COA & MSDS Available
Category   Fluorinating Reagent 
Brand Ruifu Chemical

Advantages:

How to Purchase? Please contact Dr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com  15 Years Experience? We have more than 15 years of experience in the manufacture and export of a wide range of high quality pharmaceutical intermediates or fine chemicals. Main Markets? Sell to domestic market, North America, Europe, India, Korea, Japanese, Australia, etc. Advantages? Superior quality, affordable price, professional services and technical support, fast delivery. Quality AssuranceStrict quality control system. Professional equipment for analysis include NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, K.F, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, etc. SamplesMost products provide free samples for quality evaluation, shipping cost should be paid by customers. Factory AuditFactory audit welcome. Please make an appointment in advance. MOQ? No MOQ. Small order is acceptable. Delivery Time? If within stock, three days delivery guaranteed. TransportationBy Express (FedEx, DHL), by Air, by Sea. Documents? After sales service: COA, MOA, ROS, MSDS, etc. can be provided. Custom SynthesisCan provide custom synthesis services to best fit your research needs. Payment TermsProforma invoice will be sent first after confirmation of order, enclosed our bank information. Payment by T/T (Telex Transfer), PayPal, Western Union, etc. 

FAQ:

Stable Supply: Maintain reasonable stock    

Professional Service: One stop purchasing service

Technical Support: Technology solution available

Custom Synthesis Service: Ranged from grams to kilos

Fast Delivery: If within stock, three days delivery guaranteed

High Quality: Established a complete quality assurance system

Sufficient Capacity: Sufficient facilities and technicians

OEM Package: Custom package and label available

Specifications:

Items Inspection Standards Results
Appearance White to Off-White Crystal White Crystal 
Melting Point 114.0 to 119.0℃ 115.7~118.0℃
Loss on Drying <0.50% 0.03% 
Residue on Ignition <0.20% 0.05%
Purity / Analysis Method >98.0% (HPLC)  98.87% 
Infrared Spectrum Conforms to Structure Complies      
1 H NMR Spectrum  Conforms to Structure Complies      
Conclusion The product has been tested & complies with the given specifications

133745-75-2 - Risk and Safety:

Application:

Risk Codes 36/37/38 - Irritating to eyes, respiratory system and skin. Safety Description S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S37/39 - Wear suitable gloves and eye/face protection WGK Germany 3 FLUKA BRAND F CODES 10 TSCA No Hazard Note Oxidising Agent Hazard Class IRRITANTN-Fluorobenzenesulfonimide (NFSI) (CAS: 133745-75-2), Versatile fluorinating reagent used in the fluorination of aryls, enolates, carbanions, organolithiums, etc. N-Fluorobenzenesulfonimide is a commonly used electrophilic fluorinating agent in organic synthesis to introduce fluorine into neutral organic molecules. It is also used to fluorinate nucleophilic substrates such as reactive organometallic species and malonate anions. NFSi can be synthesized by the reaction of benzenesulfonimide with fluorine. N-Fluorobenzenesulfonimide is a new, stable and mild fluorination reagent, which can introduce fluo rine atoms into the carbonyl ortho position of organic molecules, and can perform monofluorination reaction on electron-rich aromatic compounds, enol sila ne, ene Chemicalbook alcohol lithium salt, etc. The current research hotspots include Nazarov cyclization reaction catalyzed by iron or cobalt to form five-membered ring, and asymmetric catalysis of enantioselective α-fluorination. N-Fluorobenzenesulfonimide fluorinates aromatics, enolates, azaenolates and carbanions in high yield. It is used for diastereoselective fluorination of Li enolates of chiral carboximides, for directed fluorination of ortho-lithiated aromatics and for a review of electrophilic N-F fluorinating agents. Asymmteric fluorinations is effected in the presence of a Pd-BINAP catalyst system at room temperature in an ionic liquid. It is a reagent employed in a palladium-catalyzed enantioselective fluorination of t-butoxycarbonyl lactones and lactams. It is also used in the electrophilic difluorination of dihalopyridines with butyl lithium and in the direct conversion of alcohols to dibenzenesulfonamides with triphenylphosphine.  

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